In Vitro Lymphocyte Responses in Contact Hypersensitivity III

Clinical aspects of contact hypersensitivity

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Following Ribavirin Treatment In Vivo Are Contact Hypersensitivity Responses

Regulation of Lymphocyte Responses in Vitro

DNA synthesis of normal rat spleen cells in response to endotoxin increases markedly if adherent cells are first removed from the cell suspension. Addition of small numbers of purified macrophages to the cultures restores the response to a low level. T-deprived cells show these effects in very much lesser degree. Large numbers of macrophages completely suppress the response of both normal and T...

ONZIN Deficiency Attenuates Contact Hypersensitivity Responses in Mice

ONZIN is abundantly expressed in immune cells of both the myeloid and lymphoid lineage. Expression by lymphoid cells has been reported to further increase after cutaneous exposure of mice to antigens and haptens capable of inducing contact hypersensitivity (CHS), suggesting that ONZIN has a critical role in this response. Here, we report that indeed ONZIN-deficient mice develop attenuated CHS t...

Lymphocyte subsets in hypersensitivity pneumonitis.

Hypersensitivity pneumonitis (extrinsic allergic alveolitis) is the pulmonary manifestation of hypersensitivity to various categories of inhaled organic antigens. These include animal proteins from the faeces of pigeons or parakeets, or from duck and turkey feathers and antigens from various plant sources such as mouldy hay, sugar cane, bark and mushrooms. Certain drugs may also produce this re...